Season 0 of Casi Ángeles premiered on 2007-11-16.

Cielo and Nico stumble into the lives of a group of orphans exploited by Bartolomé and Justina. Cielo and Nico will help these kids while they uncover the Mansion's secrets linked to Cielo's past and to Eudamón. In that mansion, Bartolomé acts as director of the BB Foundation, which he uses as a cover for his horrible plans, which are threatened by the emergence of the heirs, Ángeles and Luz Inchausti.

No longer being subjected to Bartolomé's evil reign, the kids can live a normal life in the Hogar Mágico (ex BB Foundation) ran by Nico and Cielo, who is missing after being absorbed by the mansion's clock. New kids join the home and the CC Corporation (CC) emerges, led by Juan Cruz, who will try to break those who live in the mansion.

The kids and Justina time travel 22 years into the future after opening the book with the seven locks. With Paz, Hope and Camilo's help they'll have to figure out their mission. There's also resistance to the dictatorial government led by the Chief of Ministry.

Having saved Paz meant to succumb to a big time paradox, where the Chief of Ministry deployed the "Little Prince" protocol. From then on, the kids couldn't go back to their time and were separated. Many were captured by the Government Corporation, reset and taken to the "NE School". Others form "the Resistance" and will stop at nothing to achieve their new mission and go back home.